Archive for July, 2014

Less Toxic Transplant Treatment for Sickle Cell

Posted: July 6, 2014 by sicklecellunite in Sickle Cell

http://www.webmd.com/news/20140701/less-toxic-transplant-treatment-offers-hope-for-sickle-cell-patients

 

By Steven Reinberg

HealthDay Reporter

TUESDAY, July 1, 2014 (HealthDay News) — A new bone marrow transplant technique for adults with sickle cell disease may “cure” many patients. And it avoids the toxic effects associated with long-term use of anti-rejection drugs, a new study suggests.

This experimental technique mixes stem cells from a sibling with the patient’s own cells. Of 30 patients treated this way, many stopped using anti-rejection drugs within a year, and avoided serious side effects of transplants — rejection and graft-versus-host disease, in which donor cells attack the recipient cells, the researchers said.

“We can successfully reverse sickle cell disease with a partial bone marrow transplant in very sick adult patients without the need for long-term medications,” said researcher Dr. John Tisdale, a senior investigator at the U.S. National Heart, Lung, and Blood Institute.

In the United States, more than 90,000 people have sickle cell disease, a painful genetic disorder found mainly among blacks. Worldwide, millions of people have the disease…….. Read More